>>Our primary goal is to untangle the intercalated events of metabolism, neurodegeneration, and epilepsy utilizing our insights from studying the fatal neurodegenerative epilepsy called Lafora disease. We utilize a multidisciplinary approach that employs methodologies of cell biology, biochemistry, genetics, structural biology, and bioimformatics. We employ tissue culture cells to generate hypotheses, we test these hypotheses in vitro using purified proteins, we confirm these results using mouse models, and we define molecular mechanisms of the enzymes using structural biology.<<

Lab Meetings
2/23/11...
Presentation: MSG on current manuscripts
3/16/11...
Presentation: Dave on Current Research
3/30/11...
Presentation: Amanda on Journal Club
4/20/11...
Presentation: Travis on Current Research
more...


Home | People | About the Lab | Publications | Joining the Lab | Contact

Dr. Matthew Gentry • Phone: 859.323.8482 • Email: msge222@email.uky.edu